RESPIRATION PHYSIOLOGY: PROBLEMS |
PROBLEM SESSION ANSWERS: Problem 7
Step 1: Compute the inhaled oxygen concentration
PI-O2 = 0.21( PB - PH2O ) = 0.21 ( 200 - 47 ) = 0.21 x 153 = 32 mmHg
Step 2: Compute the alveolar PO2 using the alveolar air equation
PA-O2 = PI-O2 - PA-CO2 / R
Assuming PA-CO2 remains normal (as given) and assuming R = 0.8 gives
PA-O2 = 32 - 40/0.8 = 85 - 50 = -18 mmHg
So O2 would diffuse out of the blood in the pulmonary circulation.
Clearly, the person would not survive.
But, breathing pure oxygen at that altitude gives
Step 1: Compute the inhaled oxygen concentration
PI-O2 = 1.00( PB - PH2O ) = 1.00 ( 200 - 47 ) = 153 mmHg
Step 2: Compute the alveolar PO2 using the alveolar air equation for breathing pure oxygen:
PA-O2 = PI-O2 - PA-CO2
Assuming PA-CO2 remains normal(as given) gives
PA-O2 = 153 - 40 = 113 mmHg
This PA-O2 is even higher than when breathing air at sea level.
Clearly, the person could survive without difficulty breathing pure oxygen at this altitude.
Question: How long does the person have to put on the oxygen mask? Answer: about 20 seconds.
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